matrix产品（MatrixDB Extracellular Matrix interactions DataBase）

时间2025-05-01 17:46:13分类IT科技浏览3201

导读：MatrixDB...

MatrixDB

is a freely available database focused on interactions established by

extracellular proteins and polysaccharides. Only few databases report

protein-polysaccharide interactions and to the best of our knowledge,

there is no other interaction database focused

on the extracellular matrix. Furthermore, MatrixDB takes into account

the multimeric nature

of the extracellular proteins (e.g. collagens, laminins and

thrombospondins are multimers).

This is a concern when molecules are heterotrimeric and/or when the

multimerization process

modifies the molecular recognition properties. MatrixDB reports

interaction with individual

polypeptide chains or with multimers (permanent complexes) when

appropriate.

Data stored in MatrixDB include experimental data from our laboratory, data extracted from the literature

by manual curation, data exchanged with IMEx databases (IntAct, DIP, MINT, and BioGRID databases), and data from the Human Protein Reference Database. Data imported from other databases are restricted to extracellular proteins and their partners.

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